Brains are weird. In another life I was presenting at a neuroscience conference and one of the other speaker's spiels was focused on how forcibly "turning down" neurons' activities by optogenetically rendering them unable to fire doesn't always have the same net effect on the networks downstream of those neurons. Truly hilarious that an auditorium full of PhDs in neuroscience needed to hear that lol
Whoa, crazy, lol in another life I actually worked on a pretty similar project to what you're describing, showing that optogenetic silencing of the CA3 area of the hippocampus led to some funky downstream dynamics in CA1
Lol, for real! TBF I was in an experimental lab but didn't do much experimental work myself, I was trained as a mathematician so I mostly did computational modeling and data analysis stuff back in the day (I work on microbiome stuff now)
Brains are weird. In another life I was presenting at a neuroscience conference and one of the other speaker's spiels was focused on how forcibly "turning down" neurons' activities by optogenetically rendering them unable to fire doesn't always have the same net effect on the networks downstream of those neurons. Truly hilarious that an auditorium full of PhDs in neuroscience needed to hear that lol
Whoa, crazy, lol in another life I actually worked on a pretty similar project to what you're describing, showing that optogenetic silencing of the CA3 area of the hippocampus led to some funky downstream dynamics in CA1
Woah! Small world! No doxxing, but I wonder how many degrees of separation of authorship we are lol
Lol, for real! TBF I was in an experimental lab but didn't do much experimental work myself, I was trained as a mathematician so I mostly did computational modeling and data analysis stuff back in the day (I work on microbiome stuff now)