I think it was. I don't remember the 1500s too clearly but I think there was some headbutting between the Roman Inquisition and the Spanish Inquisition because the Spanish Inquisition was way out in the woods in terms of brutality and the scope of their activities. A lot of it was ethnic, too; the Spanish Inquisition was an anti-jewish and anti-muslim operation post Reconquista. And then there was all the violence and slavery and genocide in the New World, which saw pushback from Catholics that wasn't significant in stopping the violence but did produce a lot of writing on universal rights and stuff.