Interesting analysis from my favorite severe no nonsense physics youtuber gal (who also used to randomly post vids of her doing cover songs to peoples' general confusion lol).
Good bit at the end speculating on the material economic basis for this (useless) way of doing science. People make careers on this fluff that amounts to nothing.
Yeah, on extremely small scales we get weird results, General Relativity isn't really compatible with current quantum mechanics, and we would need new particles, at least if not modifications, to handle inflation and components of Big Bang cosmology.
Edit: I forgot to mention Dark Matter and Dark Energy would likely require two new particles, if not a more fundamental change in our understanding of these theories.
She has a blog post for common retorts to her criticism of modern theoretical particle physics, and a list of problems that would probably yield fruitful results rather than what she dubbed "pseudo problems" of the last 50 years that have yielded nothing but very ephemeral headlines in science mags.