I'm immunocompromised and continuing to stay at home and single player games really help me get through it. I've played a lot of games (especially the past 2.5 years), so dig deep and give me a good recommendation that you don't think I've played.
I'm into most genres, but not super into loot games or ubisoft open world style games. Love smaller indie titles. I love some JRPGs (Trails, DQ11, Yakuza, FF), hate others (Persona). Yeah I just said I hate persona, get over it. BoTW , Death Stranding, and Elden Ring are some of my favorite "big" games recently. The Trails JRPG series is probably my favorite overall series.
I just finished up Return to Monkey Island and really liked it (was a big fan of LucasArts adventures in the 90s), but I can't play back to pack point and click games so maybe cool off on that.
Been playing a lot of Ooblets while working out lately, so probably not gonna be receptive to any Animal Crossing / Stardew style games rn. Btw check out Ooblets if you like those kinds of games.
Rimworld has such a large mod library it's easy to keep the experience fresh.
Really any of Supergiants catalog is great, Pyre might be a bit of an acquired taste with the wizard basketball gameplay. Aside from Hades they're generally short and sweet though.
Dead Cells is a great metroidvania and is produced by a worker's co op.
Death's Door is a cute Zelda-like where you play as Dirt Owl.
Furi is very fun if you have the patience to learn boss battles and have the reflexes for it.
Neon White is a speed runner game that I probably wouldn't have tried if I hadn't heard Steve Blum voice acting the protagonist, the story is pretty mediocre but the game play is a lot of fun.