He isn't really advocating anything. He didn't write self-help books; he'd rather make things more complicated than give answers... But it's clear he's on the side of experimentation, but not necessarily of pleasure - one possibility offered in the quote above is masochism, also not everybody's thing of course.

he's asking you to forever experiment new forms of desire, of arrangements, without ever being firmly organized, beware of the ones with power that organize your desires to an inert and hierarchical form, explore without ever indulging too long in the pleasure of an instant, always follow that everchanging line to the horizon.

Pleasure is useful, sometimes, to organize yourself a little bit to help you get out of the situation that is too big for you, too complicated for you, on the search for new arrangements and desires. But beware of getting stuck in pleasure, it can kill the desire forever.

There is never an organization, an arrangement, an environment eternally adapted, each one of us must decide to bind or unbind, to build, deconstruct, rebuild, on the open path.

Pleasure interrupts pain for a moment, desire interrupts pain fully, because finally, it creates totally, a new arrangement, a new environment, step by step, eternally advancing.